Sustainability has become a critical challenge for industries, with urgent goals for decarbonization across product lifecycles, from raw material extraction to end-of-life. Sterilization of single-use products, primarily through gamma and X-ray irradiation, impacts the carbon footprint, as reflected in Life Cycle Analysis (LCA). Customers increasingly demand CO2 emission data for new products and conversions, necessitating the integration of irradiation emissions into our assessments and requiring suppliers to demonstrate emission reduction efforts. The environmental sustainability of irradiation processes is under scrutiny: the "greenness" of these methods and their long-term viability need evaluation. Furthermore, the adoption of circular economy principles introduces complexities, especially concerning the reuse of post-consumer materials or materials chemically recycled or biobased. The interaction between irradiation and polymer materials is a critical concern, as it can alter material properties, leading to radical formation and additive degradation. Could we directly apply our knowledge to a recycled irradiated polymer? Research efforts continue to establish the equivalence of gamma and X-ray sterilization and to support customer transition to these technologies. The development of a comprehensive understanding of irradiation's impact on recycled materials is essential, with the timeframe for acquiring this knowledge still undetermined. The presentation seeks to contribute to the ongoing assessment on sustainable practices within the industry for the implementation of environmentally responsible answer for single use irradiated products.